Faecal microbial transfer and complex carbohydrates mediate protection against COPD
- Creator: Budden, Kurtis F. , Shukla, Shakti D. , Patel, Vyoma K. , Donovan, Chantal , Alemao, Charlotte A. , Shen, Sj , Amorim, Nadia , Majumder, Rajib , Vanka, Kanth S. , Mason, Jazz , Haw, Tatt Johng , Tillet, Bree , Bowerman, Kare L. , Fricker, Michael , Keely, Simon , Hansbro, N , Belz, GT , Horvat, Jay , Ashhurst, T , van Vreden, C , McGuire, H , Fazekas de St Groth, B , King, NJC , Vaughan, Annalicia , Crossett, B , Cordwell, SJ , Bonaguro, L , Schultze, JL , Hamilton-Williams, EE , Mann, E , Forster, SC , Cooper, MA , Segal, LN , Chotirmall, SH , Gellatly, Shaan L. , Collins, P , Bowman, R , Fong, KM , Yang, IA , Wark, Peter A. B. , Dennis, PG , Hugenholtz, P , Hansbro, Philip M. , Wood, David L. A. , Lachner, Nancy , Idrees, Sobia , Rehman, Saima Firdous , Faiz, Alen
- Resource Type: journal article
- Date: 2024
The role of gut-lung axis in COPD: Pathogenesis, immune response, and prospective treatment
- Creator: Song, Zhi , Meng, Yifei , Fricker, Michael , Li, Xin'ao , Tian, Haochen , Tan, Yurong , Qin, Ling
- Resource Type: journal article
- Date: 2024
Adverse roles of mast cell chymase-1 in chronic obstructive pulmonary disease
- Creator: Liu, Gang , Jarnicki, Andrew G. , Paudel, Keshav R. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Wark, Peter A. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2022
Adverse roles of mast cell chymase-1 in COPD
- Creator: Liu, Gang , Jarnicki, Andrew G. , Fricker, Michael , Hansbro, Nicole G. , Dua, Kamal , Kermani, Nazanin Z. , Eapen, Mathew S. , Tiotiu, Angelica , Chung, K. Fan , Caramori, Gaetano , Bracke, Ken , Adcock, Ian M. , Paudel, Keshav R. , Sohal, Sukhwinder S. , Wark, Peter A. , Oliver, Brian G. , Hansbro, Philip M. , Lu, Wenying , Wadhwa, Ridhima , Philp, Ashleigh M. , Van Eeckhoutte, Hannelore , Marshall, Jacqueline E. , Malyla, Vamshikrishna , Katsifis, Angelica
- Resource Type: journal article
- Date: 2022
An altered sputum macrophage transcriptome contributes to the neutrophilic asthma endotype
- Creator: Fricker, Michael , Qin, Ling , Chung, Kian Fan , Gibson, Peter G. , Sánchez-Ovando, Stephany , Simpson, Jodie L. , Baines, Katherine J. , Riveros, Carlos , Scott, Hayley A. , Wood, Lisa G. , Wark, Peter A. B. , Kermani, Nazanin Z.
- Resource Type: journal article
- Date: 2022
T2-low: what do we know?: Past, present, and future of biologic therapies in noneosinophilic asthma
- Creator: Niessen, Natalie M. , Fricker, Michael , McDonald, Vanessa M. , Gibson, Peter G.
- Resource Type: journal article
- Date: 2022
Airway monocyte modulation relates to tumour necrosis factor dysregulation in neutrophilic asthma
- Creator: Niessen, Natalie M. , Gibson, Peter G. , Simpson, Jodie L. , Scott, Hayley A. , Baines, Katherine J. , Fricker, Michael
- Resource Type: journal article
- Date: 2021
Hemopexin: a novel anti-inflammatory marker for distinguishing COPD from asthma
- Creator: Winter, Natasha A. , Gibson, Peter G. , Fricker, Michael , Simpson, Jodie L. , Wark, Peter A. , McDonald, Vaness M.
- Resource Type: journal article
- Date: 2021
Molecular markers of type 2 airway inflammation are similar between eosinophilic severe asthma and eosinophilic chronic obstructive pulmonary disease
- Creator: Fricker, Michael , McDonald, Vanessa M. , Winter, Natasha A. , Baines, Katherine J. , Wark, Peter A. B. , Simpson, Jodie L. , Gibson, Peter G.
- Resource Type: journal article
- Date: 2021
Necroptosis signaling promotes inflammation, airway remodeling, and emphysema in chronic obstructive pulmonary disease
- Creator: Lu, Zhe , Van Eeckhoutte, Hannelore P. , Vanden Berghe, Tom , Brusselle, Guy G. , Horvat, Jay C. , Murphy, James M. , Wark, Peter A. , Bracke, Ken R. , Fricker, Michael , Hansbro, Philip M. , Liu, Gang , Nair, Prema M. , Jones, Bernadette , Gillis, Caitlin M. , Nalkurthi, B. Christina , Verhamme, Fien , Buyle-Huybrecht, Tamariche , Vandenabeele, Peter
- Resource Type: journal article
- Date: 2021
Neutrophilic asthma features increased airway classical monocytes
- Creator: Niessen, Natalie M. , Baines, Katherine J. , Simpson, Jodie L. , Scott, Hayley A. , Qin, Ling , Gibson, Peter G. , Fricker, Michael
- Resource Type: journal article
- Date: 2021
Sputum gene expression reveals dysregulation of mast cells and basophils in eosinophilic COPD
- Creator: Winter, Natasha A. , Gibson, Peter G. , McDonald, Vanessa M. , Fricker, Michael
- Resource Type: journal article
- Date: 2021
Sputum mast cell/basophil gene expression relates to inflammatory and clinical features of severe asthma
- Creator: Winter, Natasha A. , Qin, Ling , Gibson, Peter G. , McDonald, Vanessa M. , Baines, Katherine J. , Faulkner, Jack , Evans, Tiffany-Jane , Fricker, Michael
- Resource Type: journal article
- Date: 2021
Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment
- Creator: Niessen, Natalie M. , Gibson, Peter G. , Peters, Matthew J. , Marks, Guy B. , Baraket, Melissaa , Simpson, Jodie L. , Fricker, Michael , Baines, Katherine J. , Barker, Daniel , Yang, Ian A. , Upham, John W. , Reynolds, Paul N. , Hodge, Sandra , James, Alan L. , Jenkins, Christine
- Resource Type: journal article
- Date: 2021
Time-resolved proteomic profiling of cigarette smoke-induced experimental chronic obstructive pulmonary disease
- Creator: Skerrett-Byrne, David A. , Bromfield, Elizabeth G. , Anderson, Amanda L. , Nixon, Brett , Scott, Rodney J. , Wark, Peter A. B. , Dun, Matthew D. , Hansbro, Philip M. , Murray, Heather C. , Jamaluddin, M. Fairuz B. , Jarnicki, Andrew G. , Fricker, Michael , Essilfie, Ama T. , Jones, Bernadette , Haw, Tatt J. , Hampsey, Daniel
- Resource Type: journal article
- Date: 2021
A sputum 6 gene expression signature predicts inflammatory phenotypes and future exacerbations of COPD
- Creator: Baines, Katherine J. , Negewo, Netsanet A. , Gibson, Peter G. , Fu, Juan-Juan , Simpson, Jodie L. , Wark, Peter A. B. , Fricker, Michael , McDonald, Vanessa M.
- Resource Type: journal article
- Date: 2020
Relationship of sputum mast cells with clinical and inflammatory characteristics of asthma
- Creator: Fricker, Michael , Qin, Ling , Niessen, Natalie , Baines, Katherine J. , McDonald, Vanessa M. , Scott, Hayley A. , Simpson, Jodie L. , Gibson, Peter G.
- Resource Type: journal article
- Date: 2020
Sputum transcriptomics implicates increased p38 signalling activity in severe asthma
- Creator: Baines, Katherine J. , Fricker, Michael , McDonald, Vanessa M. , Simpson, Jodie L. , Wood, Lisa G. , Wark, Peter A. B. , Macdonald, Heather E. , Reid, Andrew , Gibson, Peter G.
- Resource Type: journal article
- Date: 2020
A sputum 6-gene signature predicts future exacerbations of poorly controlled asthma
- Creator: Fricker, Michael , Gibson, Peter G. , Peters, Matthew J. , Marks, Guy B. , Baraket, Melissa , Baines, Katherine J. , Powell, Heather , Simpson, Jodie L. , Yang, Ian A. , Upham, John W. , Reynolds, Paul N. , Hodge, Sandra , James, Alan L. , Jenkins, Christine
- Resource Type: journal article
- Date: 2019
Blood neutrophils in COPD but not asthma exhibit a primed phenotype with downregulated CD62L expression
- Creator: Lokwani, Ravi , Wark, Peter AB , Baines, Katherine J. , Fricker, Michael , Barker, Daniel , Simpson, Jodie L.
- Resource Type: journal article
- Date: 2019